Çocuk Sağlığı ve Hastalıkları Dergisi 2004 , Vol 47 , Num 3
Hypertrophic osteoarthropathy in a child with extrahepatic biliary atresia
Zarife Kuloğlu1, Aydan Kansu2, Filiz Ekici1, Fulya Demirçeken1, Ercan Tutar2, Nurten Girgin3
Ankara Üniversitesi Tıp Fakültesi 1Pediatri Uzmanı, 2Pediatri Doçenti, 3Pediatri Profesörü Hypertrophic osteoarthropathy (HO) is a syndrome characterized by clubbing of the fingers and toes, periosteal reaction and arthritis. It is rarely seen in childhood. There are a few reports in the literature of pediatric patients biliary atresia who developed HO. It has been suggested that pulmonary arteriovenous shunting plays an important role in the pathogenesis. Steroid and nonsteroid antiinflammatory therapy can be helpful in symptomatic patients. Here, we present a girl patient diagnosed as biliary atresia who developed HO in follow-up. We want to emphasize that children with chronic liver disease who present with finger clubbing or soft tissue hypertophy of the fingers should be a warning for hepatic hypertrophic osteoarthropathy (HHO). Furthermore, HHO should be considered in differential diagnosis in the cases of arthritis and arthralgia. Anahtar Kelimeler : ipertrofik osteoartropati, karaciğer yetmezliği, ekstrahepatik biliyer atrezi, hildren, hypertrophic osteoarthropathy, liver failure, extrahepatic biliary atresia.
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