Çocuk Sağlığı ve Hastalıkları Dergisi 2002 , Vol 45 , Num 3
Varicella zoster virus infection
Güler Kanra1, Ateş Kara2
Hacettepe Üniversitesi Tıp Fakültesi 1Pediatri Profesörü, 2Pediatri Uzmanı Varicella zoster virus (VZV) is a human alpha herpesvirus that causes varicella and herpes zoster. Varicella (or chickenpox), which results from primary VZV infection, is a common childhood illness associated with fever and a generalized, pruritic vesicular rash. After primary infection, VZV establishes latency in cells of the dorsal root ganglia. Reactivation from latency results in herpes zoster commonly referred to as "shingles." Herpes zoster is a localized, painful, vesicular rash involving one or adjacent dermatomes. The incidence of herpes zoster increases with age or immunosuppression. Advances have been made in understanding VZV that have led to new ways to treat and prevent VZV infections. Antiviral agents that modify the severity of varicella and herpes zoster have been developed, and a live attenuated varicella vaccine that protects against primary VZV infection is now licensed for clinical use. Here we would like to emphasize clinical findings both in varicella and zoster with complication and also indication of treatment and immunization. Anahtar Kelimeler : varisella zoster virus, suçiçeği, varisella, zoster, tedavi, aşılama, vericella zoster virus, vericella, chickenpox, shingles, treatment, vaccination
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