Çocuk Sağlığı ve Hastalıkları Dergisi 2004 , Vol 47 , Num 4
Macrophage activation syndrome due to blood transfusion in a child with systemic onset juvenile chronic arthritis
Önder Yavaşcan1, Nejat Aksu2, Ümran Kurun3, Ümit Bayol4, Fatma Nur Aktaş5
SSK Tepecik Eğitim Hastanesi 1Pediatri Başasistanı, 2Pediatri Doçenti, 3Pediatri Asistanı, 4Patoloji Doçenti, 5Patoloji Uzmanı Yavaşcan Ö, Aksu N, Kurun Ü, Bayol Ü, Aktaş FN. (Department of Pediatrics, Social Security Tepecik Training Hospital, İzmir, Turkey). Macrophage activation syndrome due to blood transfusion in a child with systemic onset juvenile chronic arthritis. Çocuk Sağlığı ve Hastalıkları Dergisi 2004; 47: 287-291.

Macrophage activation syndrome (MAS) is a life-threatening syndrome characterized by persistent fever, hepatosplenomegaly, cytopenia, coagulopathy, hypofibrinogenemia, hyperlipidemia, rapid fall in erythrocyte sedimentation rate, high levels of serum ferritin and liver enzymes and infiltration of vital organs by non-Langerhans histiocytes. This syndrome is rapidly fatal without early diagnosis and institution of therapy. The clinical and laboratory findings that occur suddenly are characteristic. In this article, we describe a three-year-old girl with systemic onset juvenile chronic arthritis who developed MAS after blood transfusion. Anahtar Kelimeler : makrofaj aktivasyon sendromu, jüvenil kronik artrit, kan transfüzyonu,macrophage activation syndrome, juvenile chronic arthritis, blood transfusion.

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