Çocuk Sağlığı ve Hastalıkları Dergisi 2003 , Vol 46 , Num 3
Difficulty in the diagnosis of myelodysplastic syndrome during childhood: a case report
Gökhan Tümgör1, İbrahim Bayram1, Atila Tanyeli2, Melek Ergin3, Oğuz Canan1, H. Levent Yılmaz4, Sevil Aşkın5, Yurdanur Kılınç2
Çukurova Üniversitesi Tıp Fakültesi 1Pediatri Uzmanı, 2Pediatri Profesörü, 3Patoloji Yardımcı Doçenti, 4Pediatri Yardımcı Doçenti, 5Biyoloji Uzmanı Myelodysplastic syndrome (MDS) constitutes 1-16% of hematological malignancies in the childhood period, and is more frequently seen between two and four years of age. It is very difficult to diagnose childhood MDS. However, there has been an increasing number of reports during the last decades on childhood MDS because of the better recognition of the disease. We present a case to draw attention to the difficulty in diagnosing MDS in early childhood. An 18-month-old girl presented with fever, hepatosplenomegaly, lymphadenopathy and pancytopenia. In addition to history and physical examination a battery of laboratory tests, including microbiological, biochemical, immunological, radiological, and metabolic studies failed to assist in diagnosis. MDS was diagnosed on third bone marrow aspiration and biopsy. The patient was lost before the initiation of chemotherapy. Anahtar Kelimeler : Miyelodisplastik sendrom, çocukluk çağı, tanı, myelodysplastic syndrome, childhood, diagnosis
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