Çocuk Sağlığı ve Hastalıkları Dergisi
2003 , Vol 46 , Num 3
Anti-tumor necrosis factor-alpha monoclonal antibody treatment in a case with persistent juvenile ankylosing spondylitis and inflammatory bowel disease
Ege Üniversitesi Tıp Fakültesi 1Pediatri Uzmanı, 3Pediatri Profesörü, Sosyal Sigortalar Kurumu İzmir Tepecik Eğitim Hastanesi 2Pediatri Doçenti
Juvenile ankylosing spondylitis and inflammatory bowel disease rarely develop simultaneously, and the treatment of the disease with disease-modifying antirheumatic drugs might be difficult. In this report we present an eight-year old boy with juvenile ankylosing spondylitis and inflammatory bowel disease resistant to combined therapy of antirheumatismal drugs because of its rarity in childhood. Anti-tumor necrosis factor-a monoclonal antibody administration, a new biological treatment, is discussed in view of the literature.
Anahtar Kelimeler :
juvenil ankilozan spondilit, inflamatuvar barsak hastalığı, anti-TNF-a monoklonal antikor, juvenile ankylosing spondylitis, inflammatory bowel disease, Anti-tumor necrosis factor-a monoclonal antibody