Çocuk Sağlığı ve Hastalıkları Dergisi 2013 , Vol 56 , Num 4
Subcutaneous fat necrosis associated with perinatal asphyxia presenting hypo-/ hypercalcemia in a newborn
*Hacer Ergin1, Metin Tan2, Kazım Küçüktaşçı3,, Şeniz Ergin4, Nagihan Yalçın5, Özmert M. A. Özdemir6
Pamukkale Üniversitesi Tıp Fakültesi 1Pediatri Profesörü, 2Pediatri Araştırma Görevlisi, 3Pediatri Uzmanı, 4Dermatoloji Doçenti, 5Patoloji Profesörü, 6Pediatri Yardımcı Doçenti *İletişim: drkkucuktasci@gmail.com Subcutaneous fat necrosis is a panniculitis rarely seen in newborns. It is characterized by indurated, erythematous plaques and nodules on the back, buttocks, thighs, cheeks, and arms. Perinatal complications including gestational diabetes, preeclampsia, asphyxia, meconium aspiration, obstetric trauma, sepsis, and hypothermia are the known risk factors. A two-day-old baby was referred to our hospital due to birth asphyxia. Respiratory distress, intracranial hemorrhage, hypocalcemia, hypoglycemia, elevated creatine kinase and C-reactive protein levels, and blood culture positivity (Streptococcus viridans) were detected on admission. The baby was treated with ventilator, antibiotic, and thrombocyte suspension. At the age of 10 days, indurated, erythematous plaques and nodules were seen on the baby’s back and cheeks. Laboratory and histopathologic investigation showed hypercalcemia, elevated 1,25-(OH)2 vitamin D, high urinary calcium/creatinine ratio, and subcutaneous fat necrosis. Hypercalcemia was treated with fluid and diuretics intravenously. Two months later, the skin lesions had improved. Serum calcium, urine calcium/creatinine ratio, and renal ultrasonography were normal. Anahtar Kelimeler : subkutan yağ nekrozu, asfiksi, yenidoğan.
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