Çocuk Sağlığı ve Hastalıkları Dergisi
2013 , Vol 56 , Num 4
Subcutaneous fat necrosis associated with perinatal asphyxia presenting hypo-/ hypercalcemia in a newborn
Pamukkale Üniversitesi Tıp Fakültesi 1Pediatri Profesörü, 2Pediatri Araştırma Görevlisi, 3Pediatri Uzmanı, 4Dermatoloji Doçenti, 5Patoloji Profesörü, 6Pediatri Yardımcı Doçenti *İletişim: drkkucuktasci@gmail.com
Subcutaneous fat necrosis is a panniculitis rarely seen in newborns. It
is characterized by indurated, erythematous plaques and nodules on the
back, buttocks, thighs, cheeks, and arms. Perinatal complications including
gestational diabetes, preeclampsia, asphyxia, meconium aspiration, obstetric
trauma, sepsis, and hypothermia are the known risk factors. A two-day-old
baby was referred to our hospital due to birth asphyxia. Respiratory distress,
intracranial hemorrhage, hypocalcemia, hypoglycemia, elevated creatine kinase
and C-reactive protein levels, and blood culture positivity (Streptococcus
viridans) were detected on admission. The baby was treated with ventilator,
antibiotic, and thrombocyte suspension. At the age of 10 days, indurated,
erythematous plaques and nodules were seen on the baby’s back and cheeks.
Laboratory and histopathologic investigation showed hypercalcemia, elevated
1,25-(OH)2 vitamin D, high urinary calcium/creatinine ratio, and subcutaneous
fat necrosis. Hypercalcemia was treated with fluid and diuretics intravenously.
Two months later, the skin lesions had improved. Serum calcium, urine
calcium/creatinine ratio, and renal ultrasonography were normal.
Anahtar Kelimeler :
subkutan yağ nekrozu, asfiksi, yenidoğan.