Çocuk Sağlığı ve Hastalıkları Dergisi 2012 , Vol 55 , Num 4
Evaluation of vitamin D levels in children with juvenile idiopathic arthritis
*Elif Çomak1, Çağla Serpil Doğan1, Arife Uslu Gökçeoğlu1, Ebru Barsal Çetiner2, Sabahat Özdem3, Mustafa Koyun4, Sema Akman5
Akdeniz Üniversitesi Tıp Fakültesi 1Pediatri Uzmanı, 2Pediatri Araştırma Görevlisi, 3Biyokimya Doçenti, 4Pediatri Doçenti, 5Pediatri Profesörü The aim of this study was to investigate the prevalence of vitamin D deficiency and factors associated with vitamin D levels in children with juvenile idiopathic arthritis (JIA). The children with JIA who had an outpatient visit between March 2011 and October 2011 were evaluated retrospectively. The patients were divided into three groups according to the 25(OH)D level as: Group 1: >20 ng/ml, Group 2: 15-20 ng/ml, and Group 3: <15 ng/ml. A total of 76 patients, 45 (59.2%) girls with a mean age of 10.0±4.2 years and median follow-up of 12 months (3-110), were included in the study. The mean serum vitamin D level was 21.6±12.7 ng/ml. Vitamin D insufficiency (15-20 ng/ ml) and deficiency (<15 ng/ml) were found in 13 (17.1%) and 28 (36.8%) patients, respectively. Serum alkaline phosphatase (ALP) and parathyroid hormone (PTH) levels were high in 23 (30.2%) and 16 (22.2%) patients, respectively. Vitamin D deficiency is common in children with JIA. 25(OH)D levels should be monitored, and vitamin D supplementation should be given. Anahtar Kelimeler : juvenil idiyopatik artrit, çocuk, D vitamini.
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