Çocuk Sağlığı ve Hastalıkları Dergisi
2012 , Vol 55 , Num 4
Evaluation of vitamin D levels in children with juvenile idiopathic arthritis
Akdeniz Üniversitesi Tıp Fakültesi 1Pediatri Uzmanı, 2Pediatri Araştırma Görevlisi, 3Biyokimya Doçenti, 4Pediatri Doçenti,
5Pediatri Profesörü
The aim of this study was to investigate the prevalence of vitamin D deficiency
and factors associated with vitamin D levels in children with juvenile idiopathic
arthritis (JIA). The children with JIA who had an outpatient visit between
March 2011 and October 2011 were evaluated retrospectively. The patients
were divided into three groups according to the 25(OH)D level as: Group 1:
>20 ng/ml, Group 2: 15-20 ng/ml, and Group 3: <15 ng/ml. A total of 76
patients, 45 (59.2%) girls with a mean age of 10.0±4.2 years and median
follow-up of 12 months (3-110), were included in the study. The mean serum
vitamin D level was 21.6±12.7 ng/ml. Vitamin D insufficiency (15-20 ng/
ml) and deficiency (<15 ng/ml) were found in 13 (17.1%) and 28 (36.8%)
patients, respectively. Serum alkaline phosphatase (ALP) and parathyroid
hormone (PTH) levels were high in 23 (30.2%) and 16 (22.2%) patients,
respectively. Vitamin D deficiency is common in children with JIA. 25(OH)D
levels should be monitored, and vitamin D supplementation should be given.
Anahtar Kelimeler :
juvenil idiyopatik artrit, çocuk, D vitamini.